[A case of non-specific infection in the pharynx and larynx assisted the confirmation by targeted next-generation sequencing technology]

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 Aug 7;59(8):865-867. doi: 10.3760/cma.j.cn115330-20240129-00057.
[Article in Chinese]

Abstract

本文报道1例发生于中年男性的由单纯疱疹病毒2型感染所致的急性咽喉炎。患者男,41岁,因“剧烈咽痛、高热2 d”就诊。初始血常规检查结果符合细菌性感染特征,但给予敏感抗生素治疗5 d无效,进一步完善相关病原学抗体检查,结果均为阴性。后采用靶向测序(targeted Next Generation Sequencing,tNGS)明确诊断感染病原体为单纯疱疹病毒2型(多引发生殖器感染,咽喉部感染少见),给予针对性抗病毒药物治疗后患者感染相关临床症明显好转,1周后痊愈。.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Herpes Simplex / diagnosis
  • Herpesvirus 2, Human / genetics
  • Herpesvirus 2, Human / isolation & purification
  • High-Throughput Nucleotide Sequencing* / methods
  • Humans
  • Larynx / virology
  • Male
  • Pharyngitis*
  • Pharynx / virology