Radical cholecystectomy without liver resection for peritoneal side early incidental gallbladder cancer

World J Gastroenterol. 2024 Aug 28;30(32):3739-3742. doi: 10.3748/wjg.v30.i32.3739.

Abstract

Gallbladder cancer (GBC) is a rare disease with a poor prognosis. Simple cholecystectomy may be an adequate treatment only for very early disease (Tis, T1a), whereas reoperation is recommended for more advanced disease (T1b and T2). Radical cholecystectomy should have two fundamental objectives: To radically resect the liver parenchyma and to achieve adequate clearance of the lymph nodes. However, recent studies have shown that compared with lymph node dissection alone, liver resection does not improve survival outcomes. The oncological roles of lymphadenectomy and liver resection is distinct. Therefore, for patients with incidental GBC without liver invasion, hepatic resection is not always mandatory.

Keywords: Early stage; Incidental gallbladder cancer; Liver resection; Radical cholecystectomy; Reoperation.

Publication types

  • Review
  • Editorial

MeSH terms

  • Cholecystectomy* / adverse effects
  • Cholecystectomy* / methods
  • Gallbladder Neoplasms* / pathology
  • Gallbladder Neoplasms* / surgery
  • Hepatectomy* / adverse effects
  • Hepatectomy* / methods
  • Humans
  • Incidental Findings
  • Liver / diagnostic imaging
  • Liver / pathology
  • Liver / surgery
  • Lymph Node Excision* / adverse effects
  • Lymph Node Excision* / methods
  • Lymphatic Metastasis
  • Neoplasm Staging
  • Peritoneum / pathology
  • Peritoneum / surgery
  • Treatment Outcome