Arthroscopy With Adipose-Derived Stromal Vascular Fraction Using a Selective Tissue Engineering Photo-Stimulation Technique for the Treatment of Mild to Moderate Knee Osteoarthritis

José Paulo Gabbi Aramburu Filho; Rafael da Rocha Macedo; Patricio Centurion; Eduardo Branco de Sousa

doi:10.1016/j.eats.2024.103015

Arthroscopy With Adipose-Derived Stromal Vascular Fraction Using a Selective Tissue Engineering Photo-Stimulation Technique for the Treatment of Mild to Moderate Knee Osteoarthritis

Arthrosc Tech. 2024 May 4;13(8):103015. doi: 10.1016/j.eats.2024.103015. eCollection 2024 Aug.

Authors

José Paulo Gabbi Aramburu Filho^{1

2}, Rafael da Rocha Macedo^{3

4}, Patricio Centurion⁵, Eduardo Branco de Sousa⁶

Affiliations

¹ Orthopaedics and Traumatology Service, Rio de Janeiro Military Police Central Hospital, Rio de Janeiro, Brazil.
² Hospital Quinta D'Or, Rio de Janeiro, Brazil.
³ Hospital IFOR-Rede D'Or São Luiz, São Bernardo do Campo, Brazil.
⁴ Discipline of Orthopaedics and Traumatology, ABC Faculty of Medicine, Santo André, Brazil.
⁵ Biomedical Sciences Investigation Institute, Ricardo Palma University, Lima, Peru.
⁶ General and Specialized Surgery Department, Faculty of Medicine, Fluminense Federal University, Niterói, Brazil.

Abstract

Osteoarthritis (OA) is characterized by articular cartilage degeneration, synovial inflammation, and subchondral bone thickening, affecting the synovial joint as an organ and leading to pain and disability. Subcutaneous stromal vascular fraction is safe and relieves pain, improves function, and repairs cartilage defects in patients with knee OA. Our goal is to describe step-by-step the arthroscopic treatment of mild to moderate knee OA with photo-stimulated stromal vascular fraction harvested from the thigh using a selective tissue engineering photo-stimulation ("One S.T.E.P.") technique.