Blood Plasma Film Multifractal Scanning in COVID-19 Consequences Diagnostics

J Biophotonics. 2024 Nov;17(11):e202400356. doi: 10.1002/jbio.202400356. Epub 2024 Sep 26.

Abstract

A 3D phase scanning method was applied to study blood plasma facies, generating layered polarization maps of the object field. The most sensitive parameters to changes in birefringence distribution were identified. Multifractal analysis using wavelet transforms and fractal dimension spectra provided specific insights into the scale self-similarity of the polarization maps. The multifractal spectra of ellipticity distributions were algorithmically derived, revealing that the third- and fourth-order statistical moments were most sensitive to changes in the supramolecular networks of the facies. These findings were successfully applied to differentiate post-COVID-19 effects with high accuracy.

Keywords: COVID‐19; blood plasma; diagnostics; polarization.

MeSH terms

  • Algorithms
  • COVID-19* / blood
  • Fractals*
  • Humans
  • Plasma* / chemistry
  • Wavelet Analysis