Mild Cognitive Impairment: Quantifying a Qualitative Disorder

Neurol Clin. 2024 Nov;42(4):781-792. doi: 10.1016/j.ncl.2024.05.007. Epub 2024 Jun 14.

Abstract

Mild cognitive impairment (MCI) has been described as a transitional state between normal aging and dementia, which can be both identified and tracked over time from qualitative and/or quantitative perspectives. Each definition of MCI involves some subjective cognitive complaint, some level of objective cognitive impairment, and generally intact daily functioning. Progression to dementia is common on follow-up in MCI, but stability and reversion to normal cognition can also occur. Quantitative methods might allow health care providers to evaluate and follow the subtle declines in MCI, as well as examine possible benefits of interventions with this at-risk condition.

Keywords: Cognitive disorders; Mild cognitive impairment; Neuropsychology; Psychometrics.

Publication types

  • Review

MeSH terms

  • Cognitive Dysfunction* / diagnosis
  • Dementia / diagnosis
  • Disease Progression
  • Humans
  • Neuropsychological Tests