Long-term Assessment of Functional Outcomes and Quality of Life in Patients Undergoing Total Knee Arthroplasty

J Pharm Bioallied Sci. 2024 Jul;16(Suppl 3):S2552-S2554. doi: 10.4103/jpbs.jpbs_237_24. Epub 2024 Jun 7.

Abstract

Background: While short-term outcomes of total knee arthroplasty (TKA) have been extensively studied, there is a need for longstanding assessments to understand the enduring impact of the procedure on patient well-being.

Methods: A retrospective cohort research to rate the longstanding functional outcomes and quality of life (QoL) in those undergoing primary TKA. Patient-reported outcomes, including SF-36 and EQ-5D scores, were collected at multiple time points postoperatively (1, 5, and 10 years). Objective assessments of functional parameters, i.e., range of motion, gait analysis, and quadriceps strength, were also recorded.

Results: Current findings demonstrate significant improvements in functional outcomes post-TKA, with sustained benefits observed over a 10-year period. Range of motion, gait parameters, and quadriceps strength showed consistent enhancements postoperatively. Moreover, QoL measures, as reflected by SF-36 and EQ-5D scores, exhibited substantial improvements following TKA and remained elevated throughout the follow-up period.

Conclusion: This research highlights the enduring effectiveness of TKA in improving both functional outcomes and QoL in patients with advanced knee arthritis.

Keywords: Functional outcomes; longstanding assessment; patient-reported outcomes; quality of life; total knee arthroplasty.