Celiac disease and nonceliac enteropathies

Curr Opin Gastroenterol. 2024 Nov 1;40(6):464-469. doi: 10.1097/MOG.0000000000001048. Epub 2024 Jun 14.

Abstract

Purpose of review: This review highlights recent research in the field of celiac disease.

Recent findings: Epidemiological studies continue to identify celiac disease-associated diseases such as inflammatory arthritis, irritable bowel syndrome, and cardiovascular disease. Recently published consensus guidelines provide recommendations for the long-term management and monitoring of patients with celiac disease. There are multiple pharmaceutical therapies for celiac disease under investigation, and recent phase I and phase II trials are reviewed here. Finally, a recent trial of patients with nonceliac gluten sensitivity demonstrates a significant nocebo effect in this condition.

Summary: Recent advances in celiac disease include the development of new clinical guidelines as well as promising new therapeutics. Continued high-quality research is needed to improve the outcomes of patients with celiac disease and nonceliac enteropathies.

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases / epidemiology
  • Cardiovascular Diseases / etiology
  • Celiac Disease* / complications
  • Celiac Disease* / diagnosis
  • Celiac Disease* / diet therapy
  • Celiac Disease* / therapy
  • Diet, Gluten-Free
  • Humans
  • Irritable Bowel Syndrome* / diagnosis
  • Irritable Bowel Syndrome* / therapy
  • Practice Guidelines as Topic