Airway bacterial colonization is associated with bronchial remodeling in severe preschool wheezers

Fabien Beaufils; Laurence Delhaes; Pauline Esteves; Marine Michelet; Cécile Bébéar; Hugues Begueret; Michael Fayon; Patrick Berger

doi:10.1111/pai.14253

Airway bacterial colonization is associated with bronchial remodeling in severe preschool wheezers

Pediatr Allergy Immunol. 2024 Oct;35(10):e14253. doi: 10.1111/pai.14253.

Authors

Fabien Beaufils^{1

2

3}, Laurence Delhaes^{1

2

3}, Pauline Esteves^{1

3}, Marine Michelet^{4

5}, Cécile Bébéar⁶, Hugues Begueret², Michael Fayon^{1

2

3}, Patrick Berger^{1

2

3}

Affiliations

¹ Centre de Recherche Cardio-thoracique de Bordeaux, Univ. Bordeaux, INSERM U1045, Pessac, France.
² CHU Bordeaux, Département de Pédiatrie, CIC-P 1401, Service de parasitologie, Service de bactériologie, Service d'Anatomopathologie, Service d'Exploration Fonctionnelle Respiratoire, Bordeaux, France.
³ INSERM, Centre de Recherche Cardio-thoracique de Bordeaux, U1045, Centre d'Investigation Clinique (CIC-P 1401), Pessac, France.
⁴ CHU Toulouse, Hôpital des Enfants, Service de pneumologie-allergologie pédiatrique, Service d'Anatomopathologie, Bordeaux, France.
⁵ University Toulouse Paul Sabatier, INSERM U1043 (CPTP), Toulouse, France.
⁶ CHU Bordeaux, Laboratoire de Bactériologie, Bordeaux, France.

PMID: 39365292
DOI: 10.1111/pai.14253

No abstract available

Keywords: asthma; bronchial biopsies; broncho‐alveolar lavage; epithelium; inflammation; smooth muscle; virus.

Publication types

Letter

MeSH terms

Airway Remodeling*
Asthma / microbiology
Bronchi* / microbiology
Child, Preschool
Female
Humans
Male
Respiratory Sounds*
Severity of Illness Index

Publication types

MeSH terms

Grants and funding