Removing interoceptive input from the kidney to the brain reduces salt appetite in DOCA hypertensive rats

Kidney Int. 2024 Dec;106(6):1181-1185. doi: 10.1016/j.kint.2024.08.033. Epub 2024 Oct 5.

Authors

Mariana R Lauar¹, Rawan N Almutlaq², Sridhatri Guntipally¹, Babatunde S Anidu², Rachel Kram¹, Jaryd Ross¹, John W Osborn¹, Alex Dayton³, Louise C Evans⁴

Affiliations

¹ Department of Surgery, University of Minnesota, Minneapolis, Minnesota, USA.
² Department of Integrative Biology and Physiology, University of Minnesota, Minneapolis, Minnesota, USA.
³ Division of Nephrology and Hypertension, University of Minnesota, Minneapolis, Minnesota, USA.
⁴ Department of Surgery, University of Minnesota, Minneapolis, Minnesota, USA. Electronic address: levans@umn.edu.

PMID: 39370041
PMCID: PMC11585427 (available on 2025-12-01)
DOI: 10.1016/j.kint.2024.08.033

Abstract

Keywords: afferent renal denervation; interoception; salt appetite.

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