A five-year-old boy with anaphylaxis reaction to gadolinium-based MR contrast medium: a case report

BMC Pediatr. 2024 Oct 15;24(1):660. doi: 10.1186/s12887-024-05144-9.

Abstract

Magnetic resonance imaging (MRI) is one of the most widely used tests in orthopedic areas. Gadolinium-based magnetic resonance (MR) contrast media are commonly used for MRI tests. They are known to be safe with little side effects and low incidence of acute adverse reactions. Although not common, immediate hypersensitivity reaction can occur in some patients after administration of gadolinium-based MR contrast media, causing skin rash, vascular edema, dyspnea, abdominal pain, hypotension, altered mental status, cardiopulmonary arrest, and even death. During a knee joint MRI test in a 5-year-old boy, anaphylaxis, a serious symptom, occured after injecting gadolinium-based MR contrast medium. Here we report this case along with a literature review.

Keywords: Anaphylaxis; Gadolinium-based Magnetic Resonance (MR) contrast media; Pediatrics; Severe acute adverse reaction.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Anaphylaxis* / chemically induced
  • Anaphylaxis* / diagnosis
  • Child, Preschool
  • Contrast Media* / adverse effects
  • Gadolinium* / adverse effects
  • Humans
  • Magnetic Resonance Imaging* / adverse effects
  • Magnetic Resonance Imaging* / methods
  • Male

Substances

  • Contrast Media
  • Gadolinium