One year outcomes following of carotid endarterectomy in different age groups: Russian multicenter study

Anton Kazantsev; Alexander Korotkikh; Roman Leader; Sergey Artyukhov; Lyudmila Roshkovskaya; Vladimir Unguryan; Maxim Chernyavin; Belov Yury

doi:10.1007/s12055-024-01753-2

One year outcomes following of carotid endarterectomy in different age groups: Russian multicenter study

Indian J Thorac Cardiovasc Surg. 2024 Nov;40(6):675-683. doi: 10.1007/s12055-024-01753-2. Epub 2024 Jun 19.

Authors

Anton Kazantsev¹, Alexander Korotkikh², Roman Leader³, Sergey Artyukhov⁴, Lyudmila Roshkovskaya⁴, Vladimir Unguryan⁵, Maxim Chernyavin⁶, Belov Yury⁷

Affiliations

¹ Kostroma Regional Clinical Hospital Named After Korolev E.I, Kostroma, Russian Federation.
² Clinic of Cardiac Surgery of the Amur State Medical Academy of the Ministry of Health of Russia, Blagoveshchensk, Russian Federation.
³ Kemerovo State Medical University, Kemerovo, Russian Federation.
⁴ City Alexander Hospital, St. Petersburg, Russian Federation.
⁵ Kostroma Oncological Dispensary, Kostroma, Russian Federation.
⁶ Clinical Hospital of the Administration of the President of the Russian Federation, Moscow, Russian Federation.
⁷ Federal State Budgetary Scientific Institution Russian Scientific Center for Surgery Named After Academician B.V. Petrovsky, Moscow, Russian Federation.

PMID: 39416342
PMCID: PMC11473465 (available on 2025-11-01)
DOI: 10.1007/s12055-024-01753-2

Abstract

Introduction: This is a retrospective analysis of the results of carotid endarterectomy (CEA) in different age groups.

Methods: This cohort, comparative, retrospective, open-label study for the period from 2008 to 2020 included 7248 patients with hemodynamically significant stenoses of the internal carotid artery (ICA), who underwent CEA. According to the classification of the World Health Organization, patients were divided into groups depending on age: up to 44 years-young age (n = 84); 45-60 years-middle age (n = 1635); 61-75-elderly age (n = 4817); over 75 years-senile age (n = 712).

Results: In terms of the frequency of hospital complications, the group of patients over 75 years of age experienced the largest number of cardiovascular events. One year after surgery, there were no significant differences in the incidence of complications between groups: death (group 1, 1.2%; group 2, 0.5%; group 3, 0.4%; group 4, 1%; p = 0.14), myocardial infarction (group 1, 1.2%; group 2, 0.3%; group 3, 0.14%; group 4, 0.3%; p = 0.12), stroke (group 1, 0%; group 2, 0.3%; group 3, 0.1%; group 4, 0.4%; p = 0.32).

Conclusion: The largest number of adverse cardiovascular events after CEA are observed among patients over 75 years of age, which is due to the high frequency of multivessel coronary lesions, atrial fibrillation, and the severity of the comorbidities. One year after surgery, there were no significant differences in the incidence of complications between groups.

Keywords: Age; Carotid endarterectomy; Eversion carotid endarterectomy; Patch; Senile age.

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