Onyx embolization for salvage hemostasis after intraoperative rupture

J Neurointerv Surg. 2024 Nov 22;16(12):1211. doi: 10.1136/jnis-2023-021402.

Abstract

Video 1 shows three cases of intraoperative rupture during aneurysm coiling. Management of intraoperative aneurysm rupture is reviewed in brief, including reversal of anticoagulation/antiplatelets, intracranial pressure control, and rapid balloon deployment for control across the aneurysm neck. However, in all three cases, contrast extravasation continues despite aneurysm coiling, reversal of anticoagulation, and maximizing medical management. This is presumed to occur when the neck of the aneurysm is the site of rupture. We review the use of a salvage technique that can be considered as a last-ditch maneuver in these scenarios, which is deployment of Onyx liquid embolic (Medtronic). Onyx is the preferred liquid embolic for this use as it is cohesive instead of adhesive. The solvent used with Onyx, dimethyl sulfoxide, is also compatible with standard balloons.1 This is relevant because a balloon is needed both for control of hemorrhage during salvage embolization and for protection of the parent vessel from the embolic material. neurintsurg;16/12/1211/V1F1V1Video 1Demonstrating the technique of Onyx embolization for salvage hemostasis after intraoperative aneurysm rupture during coiling. Three example cases are shown.

Keywords: Aneurysm; Angiography; Balloon; Complication; Hemorrhage.

Publication types

  • Case Reports
  • Video-Audio Media

MeSH terms

  • Aneurysm, Ruptured* / diagnostic imaging
  • Aneurysm, Ruptured* / surgery
  • Aneurysm, Ruptured* / therapy
  • Dimethyl Sulfoxide* / therapeutic use
  • Embolization, Therapeutic* / methods
  • Humans
  • Intracranial Aneurysm* / surgery
  • Intracranial Aneurysm* / therapy
  • Intraoperative Complications / etiology
  • Intraoperative Complications / therapy
  • Polyvinyls* / therapeutic use
  • Salvage Therapy / methods

Substances

  • Dimethyl Sulfoxide
  • Onyx copolymer
  • Polyvinyls