Discrepancy Between Functional Outcomes and Perceived Health post-ICU: A Prospective Cohort Study

Ann Am Thorac Soc. 2024 Oct 23. doi: 10.1513/AnnalsATS.202405-564OC. Online ahead of print.

Abstract

Rationale: Despite functional impairments, ICU survivors can perceive their quality of life as acceptable.

Objectives: To investigate discrepancies between calculated health, based on self-reported physical, mental and cognitive functioning, and perceived health one year after ICU admission.

Methods: Data from an ongoing prospective multicenter cohort study, MONITOR-IC, were used. Patient-reported physical, mental and cognitive functioning, and perceived health (EQ-VAS, range 0-100) one year post-ICU of patients admitted to one of eleven participating ICUs between July 2016 and September 2021 were analyzed. The relationship between functional outcomes and perceived health was modeled using linear regression. Calculated health for each patient was estimated using this model and compared to patients' perceived health, the difference reflecting a discrepancy. Based on a minimal clinically important difference of eight points, three groups were defined: patients who rated their health better than calculated (positive discrepancy), patients who rated their health worse than calculated (negative discrepancy), and patients whose perceived health was concordant with their calculated health.

Results: 2,545 patients were analyzed, of whom 45.0% (n = 1,146) showed a discrepancy between calculated and perceived health. Patients with a negative discrepancy rated their health significantly lower (median 50, IQR 36 - 66) than patients with a positive discrepancy (median 84, IQR 75 - 90). Importantly, there were no significant differences in physical, mental and cognitive functioning between patients with a negative and positive discrepancy. Patients with a negative discrepancy had a higher education level and were more often unemployed.

Conclusions: One year post-ICU, almost half of ICU survivors showed a discrepancy between calculated health and perceived health.