Pediatric Severe Febrile Thrombocytopenia Syndrome: A Case Report and Literature Review

Acta Med Okayama. 2024 Oct;78(5):401-405. doi: 10.18926/AMO/67664.

Abstract

Severe febrile thrombocytopenia syndrome (SFTS) is a tick-borne infectious disease that is endemic in parts of eastern Asia. Few pediatric cases have been reported. We describe a case of SFTS in a seven-year-old girl who presented with prolonged fever and gastrointestinal symptoms. Leukopenia and thrombocytopenia on hematology, and a history of outdoor activity led us to diagnose SFTS, although the patient had no tick bite marks. We also review the literature and discuss the characteristics of pediatric SFTS. Physicians should consider SFTS in the differential diagnosis of fever with thrombocytopenia in children living in endemic areas.

Keywords: child; severe febrile thrombocytopenia syndrome; tick-borne disease; zoonoses.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Child
  • Female
  • Humans
  • Severe Fever with Thrombocytopenia Syndrome* / diagnosis
  • Thrombocytopenia / diagnosis