Positive reinforcement-based magnet training permits social housing in catheterized squirrel monkeys

J Neurosci Methods. 2025 Jan:413:110313. doi: 10.1016/j.jneumeth.2024.110313. Epub 2024 Oct 30.

Abstract

Background: Non-human primates play a critical role in neuroscience research. Though they are social animals, laboratory study requirements can sometimes require single housing and thereby prevent social housing.

New method: To eliminate single housing and promote well-being within our squirrel monkey colony, we used positive reinforcement training in combination with magnetic/mechanical clasps and custom jackets to permit pair housing of catheterized squirrel monkeys used in behavioral studies.

Results: Adult Saimiri boliviensis boliviensis monkeys (n = 7) readily progressed through a six-stage training procedure for cooperative handling and transport from the home cage to the experimental testing rooms.

Comparison with existing methods and conclusions: Given the evidence of isolation induced stress and neurobiological consequences in multiple species, and consistent with an increased regulatory emphasis on social housing of non-human primates, the methods presented herein provide a method for handling squirrel monkeys in behavioral studies that is compatible with social housing.

Keywords: Behavioral neuroscience; Positive reinforcement training; Social housing; Squirrel monkey.

MeSH terms

  • Animals
  • Behavior, Animal / physiology
  • Catheterization / methods
  • Female
  • Housing, Animal*
  • Magnets
  • Male
  • Reinforcement, Psychology*
  • Saimiri*
  • Social Behavior
  • Social Isolation / psychology

Supplementary concepts

  • Saimiri boliviensis