Pediatric Cutaneous T-Cell Neoplasms: Clinical and Pathological Features, Updated Classifications, and Critical Differential Diagnoses

Jinjun Cheng; Birte Wistinghausen; A Yasmine Kirkorian

doi:10.1111/pde.15789

Pediatric Cutaneous T-Cell Neoplasms: Clinical and Pathological Features, Updated Classifications, and Critical Differential Diagnoses

Pediatr Dermatol. 2024 Nov 3. doi: 10.1111/pde.15789. Online ahead of print.

Authors

Jinjun Cheng^{1

2

3}, Birte Wistinghausen^{2

3}, A Yasmine Kirkorian^{3

4}

Affiliations

¹ Department of Pathology and Laboratory Medicine, Children's National Hospital, Washington, DC, USA.
² Centers for Cancer & Blood Disorders and Cancer & Immunology Research, Children's National Hospital, Washington, DC, USA.
³ The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
⁴ Division of Dermatology, Children's National Health System, Washington, DC, USA.

PMID: 39491478
DOI: 10.1111/pde.15789

Abstract

Cutaneous T-cell lymphoid neoplasms in childhood are exceedingly rare, presenting with a wide spectrum of clinical presentation and outcomes. Due to numerous clinical and pathological mimics, an integrated evaluation of clinical, histopathological, immunohistochemical, and molecular findings is critical for a diagnosis. Here, we review the clinical and pathological features, updated classifications, and critical differential diagnoses of cutaneous T-cell lymphoid neoplasms in children.

Keywords: ALCL; ICC; LyP; MF; SPTCL; WHO.

Publication types

Review