•Skeletal fragility and immobility in osteogenesis imperfecta may lead to obesity.•Bariatric surgery is an efficient treatment for severe obesity.•Bone turnover and BMD should be monitored closely during periods of rapid weight loss.•Bone protective treatment minimizes bone deterioration before weight loss.•Bariatric surgery may be considered in mild osteogenesis imperfecta.
© 2024 The Authors.