Potentially toxic elements (PTEs) in the invasive Asian clam (Corbicula fluminea) from polluted urban river areas of Bangladesh and evaluation of human health risk

Abstract

The invasive Asian clam species, Corbicula fluminea, has significant ecological and societal implications at both local and international levels due to its nutritional aspects. C. fluminea from four urban rivers in Bangladesh exhibited negative allometric growth and degree of contamination with potentially toxic elements (PTEs), which posed a concern to human health based on the AAS and USEPA risk models. The highest mean concentration of PTEs followed a decreasing order: Zn (155.08 ± 4.98 mg/kg) > Cu (53.96 ± 7.61 mg/kg) > Mn (14.29 ± 3.25 mg/kg) > Cd (2.23 ± 0.10 mg/kg) > Pb (1.64 ± 0.14 mg/kg) > As (1.51 ± 0.45 mg/kg) > Ni (1.25 ± 0.27 mg/kg) > Cr (0.65 ± 0.02 mg/kg) in C. fluminea and raising safety concerns. With the exception of Cr and Mn, all element levels were exceeded safety guideline value (SGV) (mg/kg. ww) and exhibited a strong positive correlation (p < 0.05) among the sites. The target hazard quotient of Mn is THQ > 1, and As showed a non-carcinogenic risk in children at OBR, BR, and MR site. The hazard index (HI > 1) value at the BR and MR sites indicated a public health risk associated with the clam. The target cancer risk (TCR) values for As, Cd, and Ni showed that consuming clams posed a carcinogenic risk to human health. These findings suggest that eating these clams may put consumers at significant risk for health issues related to As, Cd, Ni, and Mn exposure. The study emphasizes the need for strict monitoring and preventative measures to reduce the health risks posed by PTEs contamination in clams.

Keywords: Asian clam; Cancer risk; PTEs; Pollution.