Advanced Endoscopic Imaging for Dysplasia Characterization in Inflammatory Bowel Disease

Gastrointest Endosc Clin N Am. 2025 Jan;35(1):179-194. doi: 10.1016/j.giec.2024.07.006. Epub 2024 Oct 2.

Abstract

Recent therapeutic innovations in the management of inflammatory bowel disease (IBD) have significantly improved patient outcomes, leading to increased life expectancy and reducing the necessity for total colectomy. However, this prolonged disease duration increases the cumulative risk for dysplasia and eventually colorectal cancer development. Therefore, timely detection and correct characterization of emerging dysplastic lesions is of great importance in longstanding IBD. This narrative review aims to elucidate the current state of advanced endoscopic imaging for dysplasia characterization in inflammatory bowel disease.

Keywords: Dysplasia; Inflammatory bowel disease; Malignancy surveillance; Virtual chromoendoscopy.

Publication types

  • Review

MeSH terms

  • Colonoscopy / methods
  • Colorectal Neoplasms* / diagnostic imaging
  • Colorectal Neoplasms* / pathology
  • Humans
  • Inflammatory Bowel Diseases* / complications
  • Inflammatory Bowel Diseases* / diagnostic imaging
  • Precancerous Conditions / diagnostic imaging
  • Precancerous Conditions / pathology