Multiple-site decontamination in critically ill patients requires careful implementation

Yuetian Yu; Bin Lin; Lihui Wang; Chunhui Xu; Cheng Zhu; Yuan Gao

doi:10.1016/j.imj.2024.100142

Multiple-site decontamination in critically ill patients requires careful implementation

Infect Med (Beijing). 2024 Oct 16;3(4):100142. doi: 10.1016/j.imj.2024.100142. eCollection 2024 Dec.

Authors

Yuetian Yu^{1

2}, Bin Lin^{2

3}, Lihui Wang¹, Chunhui Xu⁴, Cheng Zhu⁵, Yuan Gao¹

Affiliations

¹ Department of Critical Care Medicine, Renji Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai 200127, China.
² Key Laboratory of Intelligent Pharmacy and Individualized Therapy of Huzhou, Huzhou 313100, Zhejiang Province, China.
³ Department of Pharmacy, Changxing People's Hospital; Changxing Branch, Second Affiliated Hospital of Zhejiang University School of Medicine, Huzhou 313100, Zhejiang Province, China.
⁴ State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
⁵ Department of Disease Prevention and Control, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai 200025, China.

Abstract

The EPIC III study showed that 52% of patients admitted to the intensive care unit (ICU) have infectious diseases and that the incidence of ICU-acquired infections is increasing, leading to longer ICU stays and higher mortality rates. Multiple-site decontamination, a type of selective decontamination program, has been associated with a reduction in the incidence of ICU-acquired infection and decreased mortality rates in some critically ill patients. However, the standardized implementation and actual effectiveness of multiple-site decontamination require further investigation.

Publication types

Editorial