Identification of the Novel HLA-DQA1*05:01:16 Allele by Next Generation Sequencing in a Chinese Individual

HLA. 2024 Nov;104(5):e15772. doi: 10.1111/tan.15772.

Abstract

HLA-DQA1*05:01:16 differs from DQA1*05:01:01:01 by two nucleotide substitutions, one in exon 4 and one in intron 1.

Keywords: HLA‐DQA1*05:01:16; new allele; next generation sequencing.

MeSH terms

  • Alleles
  • East Asian People / genetics
  • Exons
  • HLA-DQ alpha-Chains* / genetics
  • High-Throughput Nucleotide Sequencing
  • Histocompatibility Testing*
  • Humans
  • Introns

Substances

  • HLA-DQ alpha-Chains
  • HLA-DQA1 antigen