Successful management of coronary artery perforation with drug-coated balloon: a case report

BMC Cardiovasc Disord. 2024 Nov 26;24(1):680. doi: 10.1186/s12872-024-04309-9.

Abstract

Background: Coronary artery perforation (CAP) is a rare but serious complication of Percutaneous coronary intervention (PCI) with significant morbidity and mortality. Traditional management involves the use of covered stents, yet alternative interventions may be necessary. To report a unique case of CAP managed effectively with a drug-coated balloon, highlighting a novel application of this technology in emergency PCI.

Case presentation: A 73-year-old male with a history of chronic angina, hypertension, and diabetes underwent PCI for severe stenosis in the mid-left anterior descending (LAD) artery. During the procedure, a large vessel CAP occurred. Immediate management included hemodynamic stabilization via fluid resuscitation and dopamine administration, followed by the deployment of drug-coated balloons instead of the conventional covered stent to seal the perforation. The intervention successfully sealed the perforation with restoration of thrombolysis in myocardial infarction 3 flow, and the patient remained hemodynamically stable. Follow-up over six months showed no adverse cardiovascular events and normal cardiac function was maintained.

Conclusions: This case demonstrates the potential of drug-coated balloons as a feasible alternative to covered stents in managing CAP, particularly in large vessel perforations. Further research is warranted to assess the long-term safety and efficacy of this approach.

Keywords: Chronic total occlusion; Coronary artery disease; Coronary artery perforation; Drug-coated balloon; Percutaneous coronary intervention.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Angioplasty, Balloon, Coronary* / adverse effects
  • Angioplasty, Balloon, Coronary* / instrumentation
  • Cardiac Catheters
  • Cardiovascular Agents / administration & dosage
  • Cardiovascular Agents / therapeutic use
  • Coated Materials, Biocompatible*
  • Coronary Stenosis / diagnostic imaging
  • Coronary Stenosis / physiopathology
  • Coronary Stenosis / therapy
  • Coronary Vessels* / diagnostic imaging
  • Coronary Vessels* / injuries
  • Coronary Vessels* / physiopathology
  • Heart Injuries / diagnostic imaging
  • Heart Injuries / etiology
  • Heart Injuries / physiopathology
  • Heart Injuries / therapy
  • Hemodynamics
  • Humans
  • Male
  • Treatment Outcome
  • Vascular System Injuries / diagnostic imaging
  • Vascular System Injuries / etiology
  • Vascular System Injuries / therapy

Substances

  • Coated Materials, Biocompatible
  • Cardiovascular Agents