The Role of Oxytocin and Vasopressin in People with Borderline Personality Disorder: A Closer Look at Adolescents

Int J Mol Sci. 2024 Nov 9;25(22):12046. doi: 10.3390/ijms252212046.

Abstract

Borderline personality disorder constitutes a significant medical challenge. Despite the fact that its occurrence among adolescents is currently attracting increasing interest from both clinicians and researchers, there is still insufficient data on this phenomenon. The etiology and maintenance of borderline personality disorder are not yet fully comprehended. Neuropeptides, including oxytocin and vasopressin, are considered to be involved in the development of this condition. The mechanism behind the actions of these neurohormones requires further investigation. Our work aims to collect and analyze the available research and existing hypotheses on the role of oxytocin and vasopressin in people with borderline personality disorder, with special attention drawn to adolescents suffering from this condition.

Keywords: adolescents; borderline personality disorder; oxytocin; vasopressin.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Borderline Personality Disorder* / metabolism
  • Borderline Personality Disorder* / psychology
  • Humans
  • Oxytocin* / metabolism
  • Vasopressins* / metabolism

Substances

  • Oxytocin
  • Vasopressins

Grants and funding

This research received no external funding.