Background/Objectives: Anatomical variations in the biceps brachii muscle (BBM) are extremely frequent, leading to developmental and clinical implications. We studied the topography of the BBM and analyzed its correlations with other structures in the brachial region. Methods: A total of 103 cadaveric upper extremities were dissected. The length of the upper extremities was utilized as a reference line. The origin and insertion of the BBM, the coracobrachialis muscle (CBM), and the related neurovascular system were evaluated. Results: Each variable was calculated as a percentile and compared according to the presence of the considered variation; in particular, a supernumerary head of the BBM was found in 12/103 (11.65%) of upper extremities and was associated with a longer upper limb (506.25 ± 32.55 mm vs. 484.27 ± 30.41 mm, p = 0.022). When the variables were standardized by the length of the upper limb, the accessory head of the BBM was associated with the distal insertion point of the CBM (28.18 ± 3.54% vs. 30.59 ± 2.94%, p = 0.011) and BBM length (55.11 ± 2.17% vs. 58.18 ± 3.72%, p = 0.006). Other variables did not present significant differences with respect to the presence of the supernumerary head of the BBM. Conclusions: BBM variations may affect the topography of other structures, such as the length of the upper extremities, insertion of the CBM, and length of the BBM. Further studies are required to elucidate its clinical implications.
Keywords: anatomical variation; biceps brachii; coracobrachialis; supernumerary head.