Superiority of 68 Ga-Trivehexin PET/CT Over 18 F-FDG PET/CT in the Evaluation of Lymph Nodes in Patients With Breast Cancer

Halil Kömek; Yunus Güzel; İhsan Kaplan; Ece Eşsiz Yilmaz; Canan Can

doi:10.1097/RLU.0000000000005585

Superiority of 68 Ga-Trivehexin PET/CT Over 18 F-FDG PET/CT in the Evaluation of Lymph Nodes in Patients With Breast Cancer

Clin Nucl Med. 2024 Nov 20. doi: 10.1097/RLU.0000000000005585. Online ahead of print.

Authors

Halil Kömek¹, Yunus Güzel¹, İhsan Kaplan¹, Ece Eşsiz Yilmaz², Canan Can¹

Affiliations

¹ From the Department of Nuclear Medicine, Gazi Yaşargil Training and Research Hospital, University of Health Sciences, Diyarbakır, Turkey.
² Department of Pathology, Dicle University Medical School, Diyarbakır, Turkey.

PMID: 39601487
DOI: 10.1097/RLU.0000000000005585

Abstract

A patient with left upper quadrant breast cancer who had 18 F-FDG PET/CT imaging underwent 68 Ga-Trivehexin PET/CT. 68 Ga-Trivehexin PET/CT showed higher radiotracer accumulation in the primary tumor, left internal mammary lymph nodes, and axillary lymph nodes compared with 18 F-FDG PET/CT. However, Trivehexin uptake was not observed in FDG-positive lymph nodes in the mediastinum and left hilar region. Benign cytological findings were noted in the biopsy of the subcarinal lymph node. This case demonstrates that the use of 68 Ga-Trivehexin PET/CT in suspicious lymph nodes in areas difficult to biopsy in breast cancer cases can contribute to accurate staging.