Chloroma of the Cerebellopontine Angle: A Rare Presentation

World Neurosurg. 2024 Dec 13:194:123516. doi: 10.1016/j.wneu.2024.11.099. Online ahead of print.

Abstract

This article presents a case study of a 7-year-old female patient with a history of acute myelogenous leukemia, previously treated with chemotherapy. The patient developed acute right peripheral facial paralysis and right upper limb weakness, leading to the discovery of an extra-axial solid lesion at the right cerebellopontine angle. This lesion extended into adjacent structures with notable contrast enhancement and restricted diffusion on magnetic resonance imaging, indicative of chloroma, an extramedullary solid mass composed of myeloid precursor cells. The article discusses the clinical presentation and radiological findings, emphasizing the importance of magnetic resonance imaging in diagnosis. It details typical imaging characteristics of cerebellopontine angle chloromas and differentiates them from other intracranial tumors.

Keywords: Acute myelogenous leukemia; Cerebellopontine Angle; Chloroma; MRI imaging; Pediatric oncology.