Scleromyxedema and Breast-Implant Associated Lymphoma: Investigating an Unusual Clinical Association

Cureus. 2024 Nov 3;16(11):e72933. doi: 10.7759/cureus.72933. eCollection 2024 Nov.

Abstract

Scleromyxedema, a rare skin condition, is characterized by a waxy-appearing papular eruption that tends to impact middle-aged adults. Scleromyxedema is often linked to monoclonal gammopathies. However, some patients do not have a coinciding monoclonal gammopathy and experience an atypical presentation of the disease. Rarely have there been reported instances of scleromyxedema related to lymphoma. In this case report, we present a woman being evaluated for breast-implant-associated anaplastic large cell lymphoma (BIA-ALCL) who ultimately received the diagnosis of scleromyxedema.

Keywords: autoimmune skin conditions; breast implant-associated anaplastic large cell lymphoma; case report; dermatology; dermatopathology; lymphoma; oncolology; paraproteinemia; scleromyxedema; spindle cell neoplasms.

Publication types

  • Case Reports