Pathogen genomics in healthcare: overcoming barriers to proactive surveillance

Antimicrob Agents Chemother. 2024 Dec 5:e0147924. doi: 10.1128/aac.01479-24. Online ahead of print.

Abstract

Pathogen genomic surveillance in healthcare has the potential to enhance patient safety by detecting outbreaks earlier, thereby reducing morbidity and mortality. Despite benefits, there are barriers to adoption, including cost, expertise, and lack of standardized methodologies and incentives. This commentary advocates for 1) investment from healthcare payors, public health, and regulatory bodies and 2) additional research on genomic surveillance for improving patient outcomes and reducing infections. Effective implementation will require strategic investment and cross-sector collaboration.

Keywords: genomic epidemiology; infection prevention; outbreaks; surveillance.