Intermolecular (4 + 3) Cycloadditions of Oxetanyl and Azetidinyl Enolsilanes

J Org Chem. 2024 Dec 20;89(24):17910-17916. doi: 10.1021/acs.joc.4c02196. Epub 2024 Dec 7.

Abstract

We report the intermolecular (4 + 3) cycloadditions of oxetanyl and azetidinyl enolsilanes with different dienes by silylium catalysis to generate bicyclic scaffolds. These enolsilanes were competent to react with furans, cyclopentadiene, and 1,3-cyclohexadiene to deliver cycloadducts in up to 96% yields.

Publication types

  • Review