The Pleminiini tribe (Pseudophyllinae: Tettigoniidae) currently comprises 51 genera and 227 valid species with a Neotropical and Afrotropical distribution. Herein, the new monotypic genus Muscuspina Mendes gen. nov. is described with a new species, Muscuspina neblina Mendes sp. nov., distributed in the Andean montane forest of Antioquia, Colombia. Maps and natural history observations are provided.