The assessment and aetiology of drug-induced ischaemic priapism

Divyen Moodley; Anja Badenhorst; Yahya Choonara; Ahmed Adam

doi:10.1038/s41443-024-01006-1

The assessment and aetiology of drug-induced ischaemic priapism

Int J Impot Res. 2024 Dec 9. doi: 10.1038/s41443-024-01006-1. Online ahead of print.

Authors

Divyen Moodley¹, Anja Badenhorst¹, Yahya Choonara², Ahmed Adam³

Affiliations

¹ Department of Urology, Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South Africa.
² Chair and Head of Pharmacy and Pharmacology, South African DSI-NRF, Research Chair of Pharmaceutical Biomaterials, Drug Delivery and Nanomedicine, Johannesburg, South Africa.
³ Associate Professor in the Division of Urology, Department of Surgery, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. aadam81@gmail.com.

PMID: 39653776
DOI: 10.1038/s41443-024-01006-1

Abstract

Ischaemic priapism is a urological emergency characterised by a prolonged, painful erection unrelated to sexual stimulation. While several aetiological factors contribute to this condition, the pharmacological causes have gained significant attention in recent years. This narrative review aims to comprehensively assess ischaemic priapism, specifically focusing on its pharmacological aetiology. We propose an approach and assessment strategy to the numerous factors associated with pharmacologically induced ischaemic priapism. By enhancing our understanding of the pharmacological causes of this condition, healthcare professionals can improve patient management and reduce the long-term complications associated with ischaemic priapism.

Publication types

Review