Case report: Guillain-Barré syndrome following acute ischemic brainstem stroke

Front Immunol. 2024 Nov 27:15:1403561. doi: 10.3389/fimmu.2024.1403561. eCollection 2024.

Abstract

Guillain-Barré syndrome (GBS) is a heterogeneous disease, and it usually develops after an antecedent infection, while rare cases develop following a central nervous system disease. Given the indeterminacy of prodromal infection symptoms and the overlap of symptoms with other neurological disorders, a rigorous clinical and neurological examination in conjunction with history is necessary for early diagnosis and treatment of GBS. Here we present a rare case of GBS following acute ischemic stroke which was different from previous reports such as GBS following hemorrhagic stroke or head trauma. Moreover, intravenous immunoglobulin was effective in this patient after 6 months of follow-up despite the potential risk of thrombotic events.

Keywords: Guillain-Barré syndrome; acute ischemic stroke; case report; diagnosis; intravenous immunoglobulin.

Publication types

  • Case Reports

MeSH terms

  • Brain Stem
  • Guillain-Barre Syndrome* / diagnosis
  • Guillain-Barre Syndrome* / etiology
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Ischemic Stroke* / diagnosis
  • Ischemic Stroke* / etiology

Substances

  • Immunoglobulins, Intravenous

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This paper was supported by the National Natural Science Foundation of China (grant number: 82171315).