18F-DCFPyL in the Detection of Prostate Cancer Spread to the Lumbosacral Plexus

Silmara R Segala; Duncan Sutherland; Glenn Bauman; Brandon Driscoll; Joseph Chin; Jonathan Romsa; Katherine A Zukotynski

doi:10.1097/RLU.0000000000005472

18F-DCFPyL in the Detection of Prostate Cancer Spread to the Lumbosacral Plexus

Clin Nucl Med. 2024 Dec 13. doi: 10.1097/RLU.0000000000005472. Online ahead of print.

Authors

Silmara R Segala¹, Duncan Sutherland², Glenn Bauman³, Brandon Driscoll⁴, Joseph Chin⁵, Jonathan Romsa², Katherine A Zukotynski⁶

Affiliations

¹ From the Centre for Probe Development and Commercialization, Hamilton, Ontario, Canada.
² Department of Medical Imaging, London Health Sciences Centre and Western University, London, Ontario, Canada.
³ Department of Oncology, London Health Sciences Centre and Western University, London, Ontario, Canada.
⁴ Techna Institute, University Health Network, Toronto, Ontario, Canada.
⁵ Department of Surgery, Western University, London, Ontario, Canada.
⁶ Department of Medical Imaging, McMaster University, Hamilton, Ontario, Canada.

PMID: 39668496
DOI: 10.1097/RLU.0000000000005472

Abstract

In most cases, prostate cancer spreads locally to the seminal vesicles, via lymphatics to pelvic and abdominal lymph nodes, and hematogenously to the bones. Direct invasion along nerve roots is exceptionally rare but can occur. Here, we present a case with 18F-DCFPyL PET/CT images showing neoplastic involvement of the lumbosacral plexus in a patient with recurrent prostate cancer.