The Use of Zolpidem in Catatonia: A Case Report

Cureus. 2024 Nov 11;16(11):e73493. doi: 10.7759/cureus.73493. eCollection 2024 Nov.

Abstract

Catatonia is a complex neuropsychiatric syndrome characterised by abnormal psychomotor disturbance, which poses a diagnostic and treatment challenge to clinicians. It is a life-threatening condition in its severe form, termed malignant and characterised by hyperthermia and autonomic disturbances. Early recognition and treatment are important in its management. A screening instrument, such as the Bush-Francis Catatonia Rating Scale (BFCRS), can help the clinician make a prompt diagnosis. Only a few published cases describe zolpidem being used to treat this condition, with lorazepam and electroconvulsive therapy (ECT) more commonly utilised as part of established treatment protocols. We discuss a case of a 70-year-old female with treatment-resistant depression and catatonic features who was successfully managed with zolpidem. This report highlights the role and efficacy of zolpidem in the clinical management of catatonia.

Keywords: cannabis induced catatonia; excited catatonia; malignant cata; past psychiatric history and depression; public psychiatry; subtypes of catatonia.

Publication types

  • Case Reports