Regional ischaemic immune myopathy: unraveling a rare subtype of dermatomyopathy

BMJ Case Rep. 2024 Dec 15;17(12):e260865. doi: 10.1136/bcr-2024-260865.

Abstract

Regional ischaemic immune myopathy (RIIM) is a subtype of dermatomyopathy which has distinct histopathology features of regional muscle fibre necrosis and regeneration. This case report aims to provide an in-depth exploration of RIIM, emphasising its clinical features and the crucial role of muscle biopsy as a diagnostic investigation, as well as the potential role of immunomodulatory therapies.

Keywords: Autoimmunity; Muscle disease; Musculoskeletal syndromes; Paraneoplastic Syndromes; Pathology.

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • Dermatomyositis / diagnosis
  • Dermatomyositis / immunology
  • Dermatomyositis / pathology
  • Humans
  • Ischemia*
  • Muscle, Skeletal / pathology
  • Muscular Diseases / diagnosis
  • Muscular Diseases / immunology
  • Muscular Diseases / pathology