Case report: A rare case of malignant solitary fibrous tumor within the joint cavity with review of the literature

Front Oncol. 2024 Nov 29:14:1463362. doi: 10.3389/fonc.2024.1463362. eCollection 2024.

Abstract

Solitary fibrous tumors (SFTs) are classified as fibroblastic/myofibroblastic tumors that originate from CD34-positive dendritic cells and usually occur in the pleura. In this paper, we describe a case of SFT within the joint cavity of the left knee. A 60-year-old man was admitted to hospital due to swelling in the left knee for the past 8 months without relevant trauma history. X-ray, computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography-computed tomography (PET-CT) presented a large, ill-circumscribed, hypervascular, and highly enhanced mass with eccentric calcification and peripheral, intra-lesional vessels. Subsequently, the patient underwent surgical resection. Postoperative pathology confirmed the neoplastic cells to be positive for CD34, Bcl-2, and SATA6, therefore was finally diagnosed as malignant SFT. The patient developed bone metastases within 1 year after surgery. SFT in the joint cavity is rare, and it is difficult to make a preoperative diagnosis.

Keywords: computed tomography; joint; magnetic resonance imaging; positron emission tomography-computed tomography; solitary fibrous tumors.

Publication types

  • Case Reports

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The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article.