Maintenance oral steroids are not required in severe asthma

Emma Rebecca Graham; Chellan Eames; Wint Soe; Lauren Fox; Ciara Whitfield; Sumita Kerley; Ma Pantaleon; Jodi McCreery; Peter Cook; Anna Freeman; Hans Michael Haitchi; Ramesh Kurukulaaratchy; Paddy Dennison; Anneliese Day; J J Hudson-Colby; Nadia Zarif; Hitasha Rupani

doi:10.1183/23120541.00568-2024

Maintenance oral steroids are not required in severe asthma

ERJ Open Res. 2024 Dec 16;10(6):00568-2024. doi: 10.1183/23120541.00568-2024. eCollection 2024 Nov.

Authors

Emma Rebecca Graham¹, Chellan Eames¹, Wint Soe¹, Lauren Fox¹, Ciara Whitfield¹, Sumita Kerley¹, Ma Pantaleon¹, Jodi McCreery¹, Peter Cook¹, Anna Freeman^{1

2}, Hans Michael Haitchi^{1

2

3

4}, Ramesh Kurukulaaratchy^{1

2

3}, Paddy Dennison¹, Anneliese Day¹, J J Hudson-Colby¹, Nadia Zarif⁵, Hitasha Rupani^{1

2

3}

Affiliations

¹ Department of Respiratory Medicine, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
² School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
³ National Institute for Health Research Southampton Biomedical Research Centre at University Hospital Southampton NHS Foundation Trust, Southampton, UK.
⁴ Institute for Life Sciences, University of Southampton, Southampton, UK.
⁵ Department of Endocrinology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

Abstract

Protocol-guided multidisciplinary team supported steroid weaning is effective in reducing maintenance OCS use in most biologic-naïve patients with severe asthma, supporting the concept that maintenance OCS are inappropriate treatments for severe asthma https://bit.ly/4cgrJEL.