Primary Cardiac Lymphoma With Dramatic Response to Chemotherapy Diagnosed by Transvenous Biopsy

Toshiki Michishita; Osamu Inaba; Moegi Kurachi; Akiko Adachi; Shuji Momose; Yasuaki Hada; Ken Negi; Yutaka Matsumura; Tetsuo Sasano

doi:10.1016/j.jaccas.2024.102728

Primary Cardiac Lymphoma With Dramatic Response to Chemotherapy Diagnosed by Transvenous Biopsy

JACC Case Rep. 2024 Dec 4;29(23):102728. doi: 10.1016/j.jaccas.2024.102728.

Authors

Toshiki Michishita¹, Osamu Inaba¹, Moegi Kurachi², Akiko Adachi³, Shuji Momose⁴, Yasuaki Hada¹, Ken Negi¹, Yutaka Matsumura¹, Tetsuo Sasano⁵

Affiliations

¹ Department of Cardiology, Japanese Red Cross Saitama Hospital, Saitama, Japan.
² Department of Hematology, Japanese Red Cross Saitama Hospital, Saitama, Japan.
³ Department of Pathology, Japanese Red Cross Saitama Hospital, Saitama, Japan.
⁴ Department of Pathology, Saitama Medical University International Medical Center, Japan.
⁵ Department of Cardiovascular Medicine, Tokyo Medical and Dental University, Tokyo, Japan.

Abstract

Primary cardiac lymphoma is a rare disease with the potential to be fatal. This case reports a patient who developed primary cardiac lymphoma resulting in cardiac tamponade. Despite a compromised general condition, the lymphoma was diagnosed through a transvenous tumor biopsy. Chemotherapy led to significant improvement in the patient's condition. Malignant lymphoma can be treated with chemotherapy. Therefore, the performance of tumor biopsies even in patients with poor general condition enabled the initiation of treatment.

Keywords: cancer; echocardiography; imaging; shortness of breath.

Publication types

Case Reports