Giant Cell Myocarditis vs Cardiac Sarcoidosis: Reconsidering the Diagnosis With FDG PET Imaging

Ethan J Fraser; Austin Culver; Phillip H Lam; Mark Hofmeyer; Farooq H Sheikh; Richa Gupta

doi:10.1016/j.jaccas.2024.102738

Giant Cell Myocarditis vs Cardiac Sarcoidosis: Reconsidering the Diagnosis With FDG PET Imaging

JACC Case Rep. 2024 Nov 20;29(22):102738. doi: 10.1016/j.jaccas.2024.102738.

Authors

Ethan J Fraser¹, Austin Culver², Phillip H Lam^{2

3}, Mark Hofmeyer^{2

3}, Farooq H Sheikh^{2

3}, Richa Gupta^{2

3}

Affiliations

¹ Department of Internal Medicine, MedStar Georgetown University Hospital, Washington, DC, USA.
² MedStar Heart and Vascular Institute, Washington, DC, USA.
³ Department of Medicine, Georgetown University School of Medicine, Washington, DC, USA.

Abstract

Giant cell myocarditis (GCM) and cardiac sarcoidosis share clinical and histologic features, but whether they represent separate processes or lie on an inflammatory cardiomyopathy spectrum is unclear. We present a case of cardiogenic shock thought to be secondary to biopsy-proven GCM with a subsequent post-transplant diagnosis of sarcoidosis through 18-fluorodeoxyglucose positron emission tomography and biopsy.

Keywords: cardiac sarcoidosis; giant cell myocarditis; inflammatory cardiomyopathy.

Publication types

Case Reports