Organic photoelectrochemical transistor based on titanium dioxide nanorods for detection of Microcystin-LR

Abstract

A more efficient signal amplification strategy is needed to improve the performance of promising photoelectrochemical sensors (PEC). Organic photoelectrochemical transistor (OPECT) sensors are of growing interest in many fields, but their potential has not yet been widely exploited and remains a challenge. In this study, a novel organic photoelectrochemical transistor aptamer (OPECT) biosensor combining photoelectrochemical analysis and organic electrochemical transistor with AgI-TiO₂ (AgI-TNs) as photoreactive material and target-specific DNA chain reaction hybridization as signal amplifier for microcystin-LR detection was developed. The developed sensor performs highly sensitive detection with a linear range of 0.1 fg mL^-1-10 pg mL^-1 and a low detection limit of 0.079 fg mL^-1. The development of the biosensitive OPECT platform is a promising tool for MC-LR detection, meanwhile it can also be used to detect other contaminants in freshwater environments.

Keywords: AgI–TiO(2); Biosensor; Organic photoelectrochemical transistors; microcystin-LR.