Fumarate Hydratase-Deficient Renal Cell Carcinoma With Paraganglioma Detected on 18F-FDG PET/CT

Yan Deng; Limeng He; Ji Wu; Wei Zhang

doi:10.1097/RLU.0000000000005645

Fumarate Hydratase-Deficient Renal Cell Carcinoma With Paraganglioma Detected on 18F-FDG PET/CT

Clin Nucl Med. 2024 Dec 23. doi: 10.1097/RLU.0000000000005645. Online ahead of print.

Authors

Yan Deng¹, Limeng He², Ji Wu³, Wei Zhang²

Affiliations

¹ From the Departments of Pediatrics.
² Nuclear Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China.
³ Department of Nuclear Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.

PMID: 39713850
DOI: 10.1097/RLU.0000000000005645

Abstract

We report FDG PET/CT findings of fumarate hydratase-deficient renal cell carcinoma coincidence with para-aortic paraganglioma in a 27-year-old man. He presented with painless gross hematuria for 3 days. CT identified an enhancing lesion in the left kidney, suggestive of a tumor. 18F-FDG PET/CT imaging showed the mass with high FDG uptake. An adjacent FDG-avid nodule was also noted. Postoperative pathology supported a diagnosis of fumarate hydratase-deficient renal cell carcinoma of the left kidney mass, and the adjacent nodule was paraganglioma.