Spotlight on YAP: Unlocking New Insights to Overcome the Barriers to Heart Regeneration

Circulation. 2025 Jan 7;151(1):94-97. doi: 10.1161/CIRCULATIONAHA.124.072263. Epub 2024 Dec 26.

Abstract

This editorial refers to “Microtubules Sequester Acetylated YAP in the Cytoplasm and Inhibit Heart Regeneration” by Liu et al. and “YAP Overcomes Mechanical Barriers to Induce Mitotic Rounding and Adult Cardiomyocyte Division” by Morikawa et al.

Keywords: Editorials; Hippo signaling pathway; YAP-signaling pathways; cell proliferation; myocytes, cardiac; regeneration.

Publication types

  • Editorial
  • Comment