Regenerative Biomimetic Photosynthesis by Covalent-Organic Framework-Based Nanobiohybrids

Jueyi Xue; Juanfang Ruan; Karen Hakobyan; Jiangtao Xu; Kang Liang

doi:10.1002/adma.202414216

Regenerative Biomimetic Photosynthesis by Covalent-Organic Framework-Based Nanobiohybrids

Adv Mater. 2024 Dec 26:e2414216. doi: 10.1002/adma.202414216. Online ahead of print.

Authors

Jueyi Xue^{1

2}, Juanfang Ruan³, Karen Hakobyan^{1

2

4}, Jiangtao Xu^{1

2

4}, Kang Liang^{1

2

5}

Affiliations

¹ School of Chemical Engineering, The University of New South Wales, Sydney, NSW, 2052, Australia.
² Australian Centre for NanoMedicine, The University of New South Wales, Sydney, NSW, 2052, Australia.
³ Electron Microscope Unit, Mark Wainwright Analytical Centre, The University of New South Wales, Sydney, NSW, 2052, Australia.
⁴ Centre for Advanced Macromolecular Design (CAMD), The University of New South Wales, Sydney, NSW, 2052, Australia.
⁵ Graduate School of Biomedical Engineering, The University of New South Wales, Sydney, NSW, 2052, Australia.

PMID: 39726083
DOI: 10.1002/adma.202414216

Abstract

Biomimetic photosynthesis, which leverages nanomaterials with light-responsive capabilities, represents an innovative approach for replicating natural photosynthetic processes for green and sustainable energy conversion. In this study, a covalent-organic framework (COF)-based artificial photosynthesis system is realized through the co-assembly of adenosine triphosphate (ATP) synthase and a light-responsive proton generator onto an imine-based COF, RT-COF-1. This system demonstrates an ATP production rate of 0.64 µmol ATP per mg protein within 90 s of light exposure and, for the first time, exhibites regenerative ATP production through multiple light on/off cycles. Furthermore, the ATP generated by the system facilitates the biocoupling of monosaccharides into disaccharides, confirming the hybrid system's capability to convert solar energy into chemical energy in the form of organic molecules. This approach shows significant potential for renewable bioenergy generation, offering precise and reliable control over biochemical processes through artificial photosynthesis.

Keywords: ATP; artificial photosynthesis; bioenergy conversion; covalent‐organic frameworks; nanobiohybrids.

Abstract

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