Evaluating the adherent perinephric fat risk score in East Asian populations and its correlation with non-alcoholic fatty liver disease

Qin-Qi Chen; Yi Yi; Ze-Cong Ma; Qin-Li Chen; Yong-Fei Liu; Chao-Lu Lin; Hai-Feng Wang; Qin-Fu Wu

doi:10.1016/j.numecd.2024.103806

Evaluating the adherent perinephric fat risk score in East Asian populations and its correlation with non-alcoholic fatty liver disease

Nutr Metab Cardiovasc Dis. 2024 Nov 22:103806. doi: 10.1016/j.numecd.2024.103806. Online ahead of print.

Authors

Qin-Qi Chen¹, Yi Yi², Ze-Cong Ma¹, Qin-Li Chen³, Yong-Fei Liu¹, Chao-Lu Lin¹, Hai-Feng Wang¹, Qin-Fu Wu¹

Affiliations

¹ Department of Urology, Longyan First Hospital Affiliated to Fujian Medical University, Longyan, 364000, China.
² Department of Urology, Longyan First Hospital Affiliated to Fujian Medical University, Longyan, 364000, China. Electronic address: shkudo221b@gmail.com.
³ Department of Radiology, The Hospital of Zhangping City, Zhangping, 364001, China.

PMID: 39732589
DOI: 10.1016/j.numecd.2024.103806

Abstract

Background and aims: This study evaluated the predictive value of the APF risk score in East Asian patients undergoing open nephrectomy and its correlation with hypertension and NAFLD.

Methods and results: A retrospective study used the clinical data of 82 patients who underwent ON between January 2010 and December 2022. Per their APF score, patients were categorized into groups A (0-2 points) and B (3-4 points). Logistic regression analyses were used to compare the overall clinical data between the two groups and identify potential risk factors. Intraoperative APF prevalence was significantly higher in group B compared to group A (P < 0.001). Group B patients were older (63.06 ± 8.88 vs. 53.69 ± 15.21 years) and had higher incidences of hypertension (P < 0.001), diabetes (P = 0.002), and NAFLD (P < 0.001). Preoperative CT scans showed significant differences in posterior (P = 0.009) and lateral perinephric fat thickness (P < 0.001), and perinephric stranding (P < 0.001). Group B also had a higher proportion of malignant tumors (P = 0.039). Multivariate logistic regression revealed that NAFLD (OR = 9.053, P = 0.010) and hypertension (OR = 5.181, P = 0.025) were highly correlated with APF risk scores.

Conclusions: In this study, we found that the newly developed APF risk score had significant value in predicting APF in East Asian patients undergoing open nephrectomy. Additionally, NAFLD and hypertension were highly correlated with elevated APF risk scores.

Keywords: Adherent perirenal fat; Insulin resistance; Mayo adhesive probability (MAP) score; Metabolic syndrome; Non-alcoholic fatty liver disease.

Copyright © 2024 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.