Severe Diffuse Ulcerative Esophagitis Caused by Epstein-Barr Virus/Cytomegalovirus Coinfection in an Immunocompetent Individual

ACG Case Rep J. 2024 Dec 27;12(1):e01578. doi: 10.14309/crj.0000000000001578. eCollection 2025 Jan.

Abstract

Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) are important causes of viral esophagitis mainly in immunocompromised individuals. Both viruses lead to development of focal ulcerations in the esophagus. While there have been rare case reports of esophagitis in immunocompetent individuals, there has not been a single reported case of coinfection with both CMV and EBV in an immunocompetent individual and presenting with diffuse esophageal ulceration. We report a case of severe diffuse ulcerative esophagitis caused by EBV/CMV coinfection in an immunocompetent individual.

Keywords: Epstein-Barr virus; cytomegalovirus; esophagitis; infection; viral esophagitis.

Publication types

  • Case Reports