Doege Potter syndrome in patient with solitary fibrous tumor of the pleura

Abstract

Solitary fibrous tumors of pleura (SFTP) are rare neoplasms derived from mesenchymal cells of the pleura. A 63-year-old male patient, laborer by profession, presented with progressive dry cough and breathlessness for one month. Clinically he had left-sided intrathoracic mass which was confirmed by CT thorax. While in hospital, patient had recurrent episodes of hypoglycemia. Histopathological examination and immunohistochemistry of the mass revealed a SFTP. Complete surgical resection of the mass led to left lung expansion and post-operative stay was uneventful. Patient was discharged with advice for follow-up. When SFTPs are associated with recurrent hypoglycemia, which is caused by the secretion of a high-molecular-weight insulin-like growth factor 2 (IGF-2), it is referred to as the Doege-Potter syndrome (DPS).

Keywords: Doege-Potter syndrome; Recurrent hypoglycemia; Solitary fibrous tumor.