Angiotensin-converting enzyme 2 modulation of pyroptosis pathway in traumatic brain injury: A potential therapeutic target

Jinxiu Guo; Shiyuan Zhao; Xue Chu; Changshui Wang; Junjun Meng; Shanshan Wei; Jianhua Wang; Yujin Guo; Weihua Kong; Wenxue Sun; Tao Zhang; Ruili Dang; Mengqi Yang; Jing Chen; Pei Jiang

doi:10.1002/ctm2.70167

Angiotensin-converting enzyme 2 modulation of pyroptosis pathway in traumatic brain injury: A potential therapeutic target

Clin Transl Med. 2025 Jan;15(1):e70167. doi: 10.1002/ctm2.70167.

Authors

Jinxiu Guo^#^{1

2}, Shiyuan Zhao^#^{1

2}, Xue Chu^{1

2}, Changshui Wang³, Junjun Meng^{1

2}, Shanshan Wei⁴, Jianhua Wang^{1

2}, Yujin Guo^{1

2}, Weihua Kong⁵, Wenxue Sun^{1

2

6}, Tao Zhang^{1

2}, Ruili Dang^{1

2}, Mengqi Yang^{1

2}, Jing Chen^{7

8}, Pei Jiang^{1

2}

Affiliations

¹ Institute of Clinical Pharmacy, Jining First People's Hospital, Shandong First Medical University, Jining, P.R. China.
² Translational Pharmaceutical Laboratory, Jining First People's Hospital, Shandong First Medical University, Jining, P.R. China.
³ Department of Neurosurgery, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, P.R. China.
⁴ Department of Graduate, Shandong Academy of Medical Sciences, Shandong First Medical University, Jinan, P.R. China.
⁵ Institute of Central Nervous Vascular Injury and Repair, Jining Academy of Medical Sciences, Jining, P.R. China.
⁶ Department of Pharmacy, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, P.R. China.
⁷ Neurobiology Key Laboratory of Jining Medical University, Jining, P.R. China.
⁸ Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, UK.

^# Contributed equally.

No abstract available

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