Identification of lesion location and discrimination between benign and malignant findings in thyroid ultrasound imaging

Sci Rep. 2024 Dec 30;14(1):32118. doi: 10.1038/s41598-024-83888-1.

Abstract

Thyroid nodules are a common thyroid disorder, and ultrasound imaging, as the primary diagnostic tool, is susceptible to variations based on the physician's experience, leading to misdiagnosis. This paper constructs an end-to-end thyroid nodule detection framework based on YOLOv8, enabling automatic detection and classification of nodules by extracting grayscale and elastic features from ultrasound images. First, an attention-weighted DCN is introduced to enhance superficial feature extraction and capture local information. Next, the CPCA mechanism is employed to reduce the interference of redundant information. Finally, a feature fusion network based on an aggregation-distribution mechanism is utilized to improve the learning capability of fine-grained features, enhancing the performance of early nodule detection. Experimental results demonstrate that our method is accurate and effective for thyroid nodule detection, achieving diagnostic rates of 89.3% for benign and 90.4% for malignant nodules based on tests conducted on 611 clinical ultrasound images, with a mean Average Precision at IoU = 0.5 (mAP@50) of 95.5%, representing a 6.6% improvement over baseline models.

Keywords: CPCA mechanism; DCN; Feature fusion network; Lesion classification; Thyroid nodules; Ultrasound imaging; YOLOv8.

MeSH terms

  • Algorithms
  • Diagnosis, Differential
  • Humans
  • Image Interpretation, Computer-Assisted / methods
  • Thyroid Gland* / diagnostic imaging
  • Thyroid Gland* / pathology
  • Thyroid Neoplasms* / diagnostic imaging
  • Thyroid Neoplasms* / pathology
  • Thyroid Nodule* / diagnostic imaging
  • Thyroid Nodule* / pathology
  • Ultrasonography* / methods