A case of synovial sarcoma of the right mid-thigh and literature review

Oncol Rev. 2024 Dec 20:18:1445143. doi: 10.3389/or.2024.1445143. eCollection 2024.

Abstract

Synovial sarcoma (SS) is a rare and malignant mesenchymal neoplasm. We report a case of a 16-year-old Chinese female diagnosed with biphasic synovial sarcoma. The imaging features, surgical procedures and pathological results of the lesion were described in detail. Additionally, we conducted a review of the literature on synovial sarcoma of the thigh over the past 2 decades, identifying a total of 25 relevant case reports and summarizing the characteristics of these cases. Synovial sarcoma has a high degree of malignancy, with a high recurrence and metastasis rate, and a 5-year survival rate of 36%-76% and a 10-year survival rate of 20%-63%, so early detection of the lesion and preoperative differential diagnosis are of paramount importance in the treatment of patients.

Keywords: biphasic; literature review; mesenchymal neoplasm; synovial sarcoma; ultrasound.

Publication types

  • Review

Grants and funding

The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. Supported by grants from Shenzhen Second People’s Hospital Clinical Research Fund of Shenzhen High-level Hospital Construction Project (Grant No. 20223357071) and Shenzhen Key Medical Discipline Construction Fund (Grant No. SZXK052). Sanming Project of Medicine in Shenzhen (Grant No. SZSM201612027).