Eyelid Spindle Cell Lipoma: Case Report and Review of Three Patients in Literature

Clin Case Rep. 2025 Jan 7;13(1):e70097. doi: 10.1002/ccr3.70097. eCollection 2025 Jan.

Abstract

A 39-year-old woman presented a saucer-shaped mass in the left upper eyelid and underwent the extirpation at local anesthesia. Pathologically, collagen fibers, capillaries, small vessels, and CD34-positive spindle cells were dispersed among mature adipose tissues, indicative of spindle cell lipoma. Long-lasting cyst-like eyelid masses would be usually dermoid cysts, and spindle cell lipoma would be listed as a rare pathological diagnosis in differential diagnoses of cyst-like lesions in the upper and lower eyelid.

Keywords: CD34; eyelid; orbital bony edge; pathology; spindle cell lipoma.